Asbestos Laws in Ohio

Asbestos Laws in Ohio Over the past decade, Ohio was one of the nation’s most active states in the area of asbestos litigation reform. By 2000, Ohio was one of only five states that accounted for more than two-thirds of the country’s new asbestos-related case filings. This distinction prompted Ohio …

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Biomarkers accurately distinguish mesothelioma from non-cancerous tissue

Scientists have identified four biomarkers that may help resolve the difficult differential diagnosis between malignant pleural mesothelioma (MPM) and non-cancerous pleural tissue with reactive mesothelial proliferations (RMPs). This is a frequent differential diagnostic problem in pleural biopsy samples taken from patients with clinical suspicion of MPM. The ability to make …

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Lung-sparing surgery for patients with advanced mesothelioma results in prolonged survival, new study shows

Patients with advanced malignant pleural mesothelioma (MPM) treated with a combination of surgery to remove the cancer but save their lung, plus photodynamic therapy and chemotherapy, had a median survival of nearly three years, with a subset of patients living longer than seven years, according to new research published in …

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Immunotherapy with live bacterium improves response rate in malignant pleural mesothelioma

Immunotherapy with a live bacterium combined with chemotherapy demonstrated more than 90% disease control and 59% response rate in patients with malignant pleural mesothelioma (MPM), according to the results of a phase Ib trial presented today at the European Lung Cancer Conference (ELCC) 2016 in Geneva, Switzerland.1 “Malignant pleural mesothelioma …

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Discovery of four subtypes of melanoma points to new treatment approaches

Melanoma, a relatively rare but deadly skin cancer, has been shown to switch differentiation states — that is, to regress to an earlier stage of development — which can lead it to become resistant to treatment. Now, UCLA researchers have found that melanomas can be divided into four distinct subtypes …

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First immunotherapy for mesothelioma on the horizon, early research suggests

Malignant pleural mesothelioma or MPM is a rare cancer, but its incidence has been rising. This cancer is usually associated with asbestos exposure, and patients have a median life expectancy of only 13-15 months. All patients relapse despite initial chemotherapy, more than 50% of them within six months after stopping …

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How melanoma tumors form

Melanoma cells move quickly, extending cables to reel in other cells and form tumors. The panels show how individual melanoma cells came together to build a tumor in just four hours.   There’s a reason why melanoma, the most serious type of skin cancer, is so aggressive. You just need …

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New therapeutic opportunity for the treatment of resistant malignant melanoma

New therapeutic opportunity for the treatment of resistant malignant melanoma A team of researchers led by Dr Pierre Close, WELBIO researcher at the ULiège GIGA Institute and Dr Francesca Rapino has uncovered a new therapeutic opportunity in the treatment of malignant melanoma that acquired resistance to targeted therapies. In collaboration …

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Study reveals how melanoma spreads

Cancerous tumors are voracious. Once they have consumed all the oxygen and nutrients in the original tumor site, the cancer cells travel to other parts of the body (metastasize) to find more nourishment. Searching for clues about how the body signals the lack of oxygen in melanoma skin cancer, National …

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Glycans at the ‘I’ of the storm in humoral immunity and melanoma progression

Two new studies have unveiled how a peculiar molecule impacts how antibody-producing cells develop and function as well as how normal melanocytes progress to melanoma malignancy. “These findings on fundamental immunology and melanoma development originate from totally different areas of research, though have intersected at the bench,” said Charles Dimitroff, …

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